Hi Colin
I am by no means an "electronics" guy and am lucky enough to have a "best mate" who is a pro amp tech.
I buy my valves from him at mates rates, I then take the amp apart and after I put in the new tubes after cleaning the valve bases, he
sets the bias for me, while I watch him and make him a cup of tea (I also save up all the packs of biscuits I get when I'm working away and "dump them on him and his guitar building business partner - bribery works!!)
Ive watched him do it and beforehand read up about it on forums etc. The last one I did was my MM amp and they give full instructions on how to do it.
One of the problems is, that when you take amps out of their cabinets, wheteher they are combos or heads, they are awkward to work on, on the bench. This is because you invariably need to get access to various places on the PCB / valve bases to check the values. When an amp is "naked", you usually find that the tubes/valves protrude more than the transformers , so you need to have blocks of wood on the bench to sit the chassis on - otherwise you will smash the valves.
Some amps "don't need biasing" - like the Mesa Boogies as previously stated. In this case you don't need to buy their valves - you can use valves that are matched. Mesas's can be modded to give you an option to manually change the bias - but that is nothing to do with your query.
Whilst I'm in rambling mode, thare are now amps on the market that are "intelligent" and have a box of tricks built into them so that you could in theory run mis matched valves and tweak the amp quite easily - it's akin to the concept of modern cars that you can interogate via a "plug and laptop".
For peace of mind Col, get it done - see if you can watch it being done? My mate charges £30 an hour bench time and the whole job can take between 30 - 40 mins - strip down, clean valve bases, bias and re assembly.
I generally leave my amp on for a few hours, whilst in his workshop and play my guitar through it - it gives the amp soak time and you are not biasing cold.