DrKev
Moderator
As mentioned by racerx above, friction is the enemy of tuning stability, so lubrication is key. That means in the slot at the nut and the top of the saddles. But no strings stay perfectly in tune very long especially under gigging conditions. The low E string is one of the lowest tension strings of the set which means is more prone to go out of tune than other strings so we notice it first. My low E string usually ends up going sharp and I suspect tuning down to pitch may help a little.The other thing ive noticed is that my low E goes out of tune quite a bit (especially during gigs), is there anything I can troubleshoot there?
Re: stratitis, I don’t think that’s what Gemmy is talking about here. Stratitis can be an issue with single coils with highly magnetic pole pieces (usually AlNiCo 5) set too close to the strings, especially playing high up the neck. But as long as the distance from the bottom of the low E string (held down at last fret) to the pole pieces are no closer than 2.4 mm or 3/32” it won’t be an issue.
Maybe some people think it sounds worse on the bridge pickup, but the induction of the pickup has nothing to do with it.