You would need to get a device like a trem-setter or equivalent to "block" the bridge. You would then however lose the ability to use the tremolo to its full ability. Normal floating tremolos cannot change tunings on the fly without having to retune all the strings. The EVH "D-tuna" only works because the tremolo on those guitars is dive only.
Another approach is to block the trem (make it down only) by putting something in the cavity that restricts the movement of the bridge.
I've used blocks of wood taped to the trem cavity wall in the past. (On a different guitar with a floating Floyd, but it's the same idea.) You can be creative there.