NorMally I'm a guitar player but I have a fretless Sterling Piezo so here goes.
Strings? That's easy. EB Pinks. I understand that is what the factory puts on them and for fretless there is just the right amount of mwah. (For me anyway) That also considers into the equation the amount of string roughness on both fingers and fret boards. Also I find the EB strings to just be so consistant. I have just gotten use to having great long lasting strings all the time.
The piezo equipped guitars have the potential to make some one run in the room and ask "Who's shredding on the Martin!?!" The Piezos on the Sterling won't make some one ask, "Who's thumping on the upright?" But it does move in that direction. I guess I could say, Kinda warm and acoustic-y. Wile Reverb + bass (to me) equals mud; adding just a
touch really gives a good big room feel for the piezo pup on the Sterling.
Setup is just like any other bridge. However, the density of the string saddles (again to me) feels just a little different. Not better or worse, just different. After playing piezo equipped bridges on guitars for what I have, I feel I prefer them.
Another noteworthy item:
Just because the piezo is there doesn't mean you have to use it. But when it is the right tool it sure is nice to have.
For the piezo guitars, I (and most other guitarists) really prefer the piezo signal go to an amp different from the one that the magnetic pups are going through. Usually an acoustic amp or a small PA (with effects built in of course cause we guitar players hide our lack of skillz behind cool effects

) The basses don't provide that option directly but that might be fun to explore.
Rattling and buzzing are things I don't worry about much on the fretless. (duh) But on the guitar that only is an issue when the tremolo gets used so hard that the string loses contact with the bridge. After I did that a couple of times I learned what the limits were pretty quickly. A good set up on your instrument makes this a non issue.
Bottom Line:
The Sterling Piezo add a fantastic element that you can't get from the mag pups. The only adaption necessary is getting use to having another tonal possibility. And that's easy to do.
Thanks for letting me share