"Tone suck" is kind of a blanket phrase people use that doesn't accurately describe the problem.
A lot of people use volume pedals between their guitar and pedals/amp. When you do that with a passive guitar, the extra resistance from the volume pedal affects the impedance the pickups see. It's like adding another 250k volume pot to your guitar- the extra resistance (in parallel) from the VP lowers the overall resistance from your pots, which affects the resonant peak of the frequencies from your pickups.
Similar to the tonal change you get from replacing 500k pots with 250k pots ... everything gets a little less bright. This effect is also dependant on the length of your guitar cable, since it interacts with the capacitance of your cable.
Anyhow- that's usually what people are referring to. To some, it's not a problem. If it is, the way to avoid any tonal effect is to use the 25k verion of the pedal and put it after a buffered pedal (or in your effects loop), so it's isolated from the guitar.
Hope that helps.