Negative polarity? Like it is putting the signal on the ground or something like that? That doesn't make any sense, and in that case it wouldn't work with ANY amp, if I understand that correctly.
If anything this sounds like the old "Active preamps don't play well with wireless systems / etc" thing. A lot of fancy electronic modellers and such use stereo input jacks, which is not uncommon, however many of them also decide to put a muting circuit or something on the "ring" area contact. I believe that the design of the LK100 may also do the same thing, using continuity to ground to tell the preamp when to turn on, or something like that. This could be interfering with the ability of the preamp to know it is plugged in, so the guitar never turns on, and you get no signal.